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WORLD HEALTH ORGANIZATIONINTERNATIONAL AGENCY FOR RESEARCH ON CANCERLISTS OF IARC EVALUATIONS ACCORDING TO IARC MONOGRAPHSIARC, Lyon 1993 `Occupational sources' column edited by IPCS, Geneva, 1993 Any comments related to the IARC Monographs should be sent to Dr. H. Vainio, Chief, Unit of Carcinogen Identification and Evaluation, International Agency for Research on Cancer
Address: 150 cours Albert Thomas
69372 Lyon Cedex 08
France
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Group 1 The agents and industrial processes which have been evaluated by
IARC Monographs Programme as being carcinogenic to humans.
Group 2A The agents and industrial processes which have been evaluated by
IARC Monographs Programme as being probably carcinogenic to humans.
Group 2B The agents and industrial processes which have been evaluated by
IARC Monographs Programme as being possibly carcinogenic to humans.
________________________________________________________________________________
Agent/Industrial process CAS Number Occupational
sources
________________________________________________________________________________
Group 1 Carcinogenic to humans
Aflatoxins (1993)(a) 1402-68-2 Feedstuff contaminants,
mycotoxins
4-Aminobiphenyl 92-67-1 Rubber manufacture
/1.,p.1292/f
Arsenic and arsenic compounds(b) 7440-38-2 Drug, pesticide
Asbestos 1332-21-4 Roofing, friction
material
Azathioprine 446-86-6 Drug
Benzene 71-43-2 Solvent, raw material
Benzidine 92-87-5 Raw material, impurity
Beryllium and beryllium compounds(d) 7440-41-7 Raw material,
electronics industry
N,N-Bis(2-chloroethyl)-2-naphthylamine
(Chlornaphazine) 494-03-1 Drug
Bis(chloromethyl)ether and 542-88-1 Laboratory chemical
chloromethyl methyl ether (technical-grade) 107-30-2
1,4-Butanediol dimethanesulfonate (Myleran) 55-98-1 Antineoplastic agent
Cadmium and cadmium compounds(d) 7440-43-9 Raw material
Chlorambucil 305-03-3 Antineoplastic agent
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)
-1-nitrosourea 13909-09-6 Antineoplastic agent
(Methyl-CCNU) /3.,p.191/
Chromium(VI) compounds (1990) Pigment manufacturing
/1.,p.470/
Ciclosporin (1990) 79217-60-0 Drug /2.,91-527/
Cyclophosphamide 50-18-0 Antineoplastic agent
Diethylstilboestrol 56-53-1 Drug
Erionite 66733-21-9 Natural
mineral fibre
/2.,pp.88-936/
Melphalan 148-82-3 Antineoplastic agent
8-Methoxypsoralen (Methoxsalen) plus
ultraviolet radiation 298-81-7 Dermatological drug
/4.,p.243/
MOPP and other combined chemotherapy
including alkylating agents Antineoplastic agents
Mustard gas (Sulfur mustard) 505-60-2 War gas
/2.,90-110/
2-Naphthylamine 91-59-8 Dye manufacturing
Nickel compounds (1990) Pigment, batteries,
impurity
Oestrogen replacement therapy Hormones /1.,p.1666/
Oestrogens, nonsteroidal(b) Hormones,
pharmaceutical
industry /1.,p.1666/
Oestrogens, oesteroidal(b) Hormones,
pharmaceutical
industry /1.,p.1666/
Oral contraceptives, combined(c) Hormones
Oral contraceptives, sequential Hormones
Radon and its decay products (1988) 10043-92-2 Mining
Solar radiation (1992)
Talc containing asbest-form fibres Extenders in paints
and ceramic products
/1.,p.2141/
Thiotepa (1990) 52-24-4 Antineoplastic agent
/2.,91-572/
Treosulfan 299-75-2 Antineoplastic agent
Vinyl chloride (monomer) 75-01-4 Plastic industry
Mixtures
Alcoholic beverages (1988)
Analgesic mixtures containing phenacetin Drugs
Betel quid with tobacco
Coal-tar pitches 65996-93-2 Raw material
Coal-tars 8007-45-2 Drug, raw material
Mineral oils, untreated and mildly treated Use of crude
oil distillates
/2.,91-960/
Salted fish (Chinese-style) (1993)
Shale-oils 68308-34-9
Soots
Tobacco products, smokeless
Tobacco smoke
Exposure circumstances
Aluminium production
Auramine
Boot and shoe manufacture and repair
Coal gasification
Coke production
Furniture and cabinet making
Haematite mining (underground) with exposure to radon
Iron and steel founding
Isopropanol manufacture, strong-acid process
Magenta, manufacture of (1993)
Painter, occupational exposure (1989)
Rubber industry
Strong-inorganic-acid mists containing sulfuric acid (1992)
________________________________________________________________________________
Agent/Industrial process CAS Number Occupational
sources
________________________________________________________________________________
Group 2A Probably carcinogenic to humans
Acrylonitrile 107-13-1 Raw material
Adriamycind 23214-92-8 Antineoplastic agent
/2.,pp.82-736/
Androgenic (anabolic) steroids Drugs
Azacitidine (1990)(d) 320-67-2 Antineoplastic agent
/2.,pp.91-572/
Benz[a]anthracene(d) 56-55-3 Impurity
Benzidine-based dyes(d) Dyes
Benzo[a]pyrene(d) 50-32-8 Impurity
Bischloroethyl nitrosourea (BCNU) 154-93-8 Antineoplastic agent
1,3-Butadiene (1992) 106-9-90 Manufacture of
synthetic rubber
/1.,p.347/
Captafol (1991)(d) 2425-06-1 Fungicides, pesticides
/1.,pp.927-1616/
Chloramphenicol (1990)(d) 56-75-7 Antibiotics /1.,p.171/
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea 13010-47-4 Antineoplastic agent
(CCNU)(d)
para-Chloro-ortho-toluidine and
its strong acid salts (1990)(d) 95-69-2 Synthesis of organic
dyestuffs
/1.,pp.146-147/
Chlorozotocin (1990)(d) 54749-90-5 Antineoplastic agent
/2.,pp.91-572/
Cisplatin(d) 15663-27-1 Antineoplastic agent
/5.,II/p.125/
Dibenz[a,h]anthracene(d) 53-70-3 Coal-tar /1.,p.1765/
Diethyl sulfate (1992)(d) 64-67-5 Raw material,
laboratories
Dimethylcarbamoyl chloride(d) 79-44-7 Laboratories
Dimethyl sulfate(d) 77-78-1 Raw material,
laboratories
Epichlorohydrin(d) 106-89-8 Epoxyres in products,
raw material,
laboratories
Ethylene dibromide(d) 106-93-4 Soil fumigant,
leaded gasoline
/1.p.623/
Ethylene oxide 75-21-8 Pesticide,
intermediate
N-Ethyl-N-nitrosourea(d) 759-73-9 Laboratory synthesis
of diazoethane
/6.,p.192/
Formaldehyde 50-00-0 Preservative,
disinfectant, textile,
wood/timber industry,
raw material
IQ(d) (2-Amino-3-methylimid-azo[4,5-f]
-quinoline) (1993) 76180-96-6 Grilled fish
and meat
/2.,pp.92-1997/
5-Methoxypsoralend 484-20-8 Dermatological agent
/4.,p.243/
4,4'-Methylene bis(2-chloroaniline)
(MOCA) (1993) 101-14-4 Polyurethane
industry, curing agent
N-Methyl-N'-nitro-N-nitrosoguanidine
(MNNG)(d) 70-25-7 Laboratory agent
/2.,pp.92-1997/
N-Methyl-N-nitrosourea(d) 684-93-5 Laboratory synthesis
of diazomethane
/21.,p.192/
Nitrogen mustar(d) 51-75-2 Basis for some
antineoplastic agents
N-Nitrosodiethylamine(d) 55-18-5 Laboratories
N-Nitrosodimethylamine(d) 62-75-9 Laboratories,
pollutant
Phenacetin 62-44-2 Drug
Procarbazine hydrochloride(d) 366-70-1 Antineoplastic agent
/2.,pp.85-1341/
Propylene oxide(d) 75-56-9 Production of propylene
glycol /1.,p.771/
Silica, crystalline 14808-60-7 Ceramic
industry /1.,p.2034/
Styrene oxide 96-09-3 Epoxy resin additive
/7/
Tris(2,3-dibromopropyl)phosphate 126-72-7
Ultraviolet radiation A (1992)(d) Solar radiation
Ultraviolet radiation B (1992)(d) Solar radiation
Ultraviolet radiation C (1992)(d) Welding operation,
laser
Vinyl bromided 593-60-2 As an intermediate
in organic synthesis,
manufacture of
polymers /8.,p.135/
Mixtures
Creosotes 8001-58-9 Wood preservative for
roofing
Diesel engine exhaust (1989)
Hot mate (1991) Beverage
Non-arsenical insecticides, spraying
and Occupational exposures in application of (1991)
Polychlorinated biphenyls (PCB) 1336-36-3 Limited application in
capacitors
Exposure circumstances
Art glass, glass containers and pressed ware (manufacture of) (1993)
Hairdresser or barber (1993)
Petroleum refining (1989)
Sunlamps and sunbeds (1992)
________________________________________________________________________________
Agent/Industrial process CAS Number Occupational
sources
________________________________________________________________________________
Group 2B Possibly carcinogenic to humans
A-a-C; (2-Amino-9H-pyrido[2,3-b]indole) 26148-68-5 Grilled food,
tobacco smoke
/9.,p.294/
Acetaldehyde 75-07-0 Manufacture of acetic
acid and ethyl
acetate /1.,p.36/
Acetamide 60-35-5 As a solvent for
organic compounds,
plasticizer /1.,p.139/
Acrylamide 79-06-1 Manufacture of
acrylamide polymers
/1.,p.138/
AF-2; [2-(2-Furyl)-3-(5-nitro-2-furyl)-
acrylamide] 3688-53-7 Ex-food
preservative
/10.,p.48/
Aflatoxin M1 (1993) 6795-23-9 Found in the milk cows
fed toxic meals /11/
para-Aminoazobenzene 60-09-3 Dyes /1.,p.231/
ortho-Aminoazotoluene 97-56-3 Dyes /1.,p.231/
2-Amino-5-(5-nitro-2-furyl)-1,3,4-
thiadiazole 712-68-5 Drug /12.,p.39/
Amitrole 61-82-5 Herbicide
ortho-Anisidine 90-04-0 Laboratories
Antimony trioxide (1989) 1309-64-4 Tartar emetic, paint
pigment /1.,p.177/
AramiteR 140-57-8 Pesticide
Atrazine (1991) 1912-24-9 Herbicide /1.,p.1626/
Auramine (technical-grade) 492-80-8 Dye manufacture
/2.,pp.80-121/
Azaserine 115-02-6 Antineoplastic agent
Benzo[b]fluoranthene 205-99-2 Impurity
Benzo[j]fluoranthene 205-82-3 Impurity
Benzo[k]fluoranthene 207-08-9 Impurity
Benzyl violet 4B 1694-09-3 Textile dye
/13.,p.155/
Bleomycinse(e) 11056-06-7 Antineoplastic drug
/12.,p.34/
Bracken fern
Bromodichloromethane (1991) 75-27-4 Intermediate
solvent /5.,II/23/
Butylated hydroxyanisole (BHA) 25013-16-5 Food additive
/2.,pp.87-1414/
b--Butyrolactone 3068-88-0 Laboratories
Caffeic acid (1993) 331-39-5 Constituent of plants
/11.,p.207/
Carbon-black extracts Manufacture of natural
and synthetic rubber
Carbon tetrachloride 56-23-5 Solvent, raw material
Ceramic fibres (1988) Use in manufacture of
paper felts, furnace
/2.,91-1961/
Chlordane (1991) 57-74-9 Pesticide
Chlordecone (Kepone) 143-50-0 Pesticide
Chlorendic acid (1990) 115-28-6 Chemical intermediate
in the manufacture of
unsaturated polyester
resins /2.,pp.90-1979/
a-Chlorinated toluenes Intermediates
para-Chloroaniline (1993) 106-47-8 Dye industry
Chloroform 67-66-3 Solvent, raw material
Chlorophenols Fungicides,
bactericides
/1.,p.1673/
Chlorophenoxy herbicides Herbicides
4-Chloro-ortho-phenylenediamine 95-83-0 Hair-dye component
/14.,p.83/
CI Acid Red 114 (1993) 6459-94-5 Dye
CI Basic Red 9 (1993) 569-61-9 Dye
CI Direct Blue 15 (1993) 2429-74-5 Dye
Citrus Red No. 2 (CI 12156) 6358-53-8 Dye
Cobalt and cobalt compounds (1991) 7440-48-4 Manufacture of magnets
/1.,p.493/
para-Cresidine 120-71-8 Dye manufacturing
Cycasin 14901-08-7 Naturally occurring
toxin, seeds, roots
and leaves of cycad
plants /15.,p.122/
Dacarbazine 4342-03-4 Antineoplastic drug
/16.,p.35/
Dantron (Chrysazin; 1,8-
Dihydroxyanthraquinone)(1990) 117-10-2 Drug/2.,pp.91-572/
Daunomycin 20830-81-3 Antineoplastic agent
DDT (para,para'-DDT) (1991) 50-29-3 Pesticide
N,N'-Diacetylbenzidine 613-35-4 Dye manufacturing
2,4-Diaminoanisole 615-05-4 Dye manufacturing,
hair dye
4,4'-Diaminodiphenyl ether 101-80-4 Dye manufacturing
2,4-Diaminotoluene 95-80-7 Dye manufacturing,
raw material, hair dye
Dibenz[a,h]acridine 226-36-8 Pollutant/1.,p.460/
Dibenz[a,j]acridine 224-42-0 Pollutant /1.,p.460/
7H-Dibenzo[c,g]carbazole 194-59-2 Tobacco smoke
/17.,p.318/
Dibenzo[a,e]pyrene 192-65-4 Diesel and gasoline
engine exhaust fumes
/18.,p.33/
Dibenzo[a,h]pyrene 189-64-0 Diesel and gasoline
engine exhaust fumes
/18.,p.33/
Dibenzo[a,i]pyrene 189-55-9 Diesel and gasoline
engine exhaust fumes
/18.,p.33/
Dibenzo[a,l]pyrene 191-30-0 Diesel and gasoline
engine exhaust fumes
/18.,p.33/
1,2-Dibromo-3-chloropropane 96-12-8 Pesticide
para-Dichlorobenzene 106-46-7 Fumigants,
insecticides
/1.,p.460/
3,3'-Dichlorobenzidine 91-94-1 Raw material, dye
manufacturing
3,3'-Dichloro-4,4'-diaminodiphenyl ether 28434-86-8 Dye, raw material
1,2-Dichloroethane 107-06-2 Solvent, raw material
Dichloromethane (Methylene chloride) 75-09-2 Solvent
1,3-Dichloropropene (technical-grade) 542-75-6 Pesticides
/2.,pp.88-1251/
Dichlorvos (1991) 62-73-7 Pesticide
Diepoxybutane 1464-53-5 Raw material,
laboratories
Di(2-ethylhexyl)phthalate 117-81-7 Plastic industry
/1.,p.1691/
1,2-Diethylhydrazine 1615-80-1 Laboratory chemical
/19.,p.154/
Diglycidyl resorcinol ether 101-90-6 Epoxy resin,
aircraft equipment
industry /20.,p.154/
Dihydrosafrole 94-58-6 Chemical intermediate
for manufacture of
piperonyl butoxide
/15.,p.235/
Diisopropyl sulfate (1992) 2973-10-6 Manufacturing of
isopropanol
3,3'-Dimethoxybenzidine (ortho-Dianisidine) 119-90-4 Dye, laboratories
para-Dimethylaminoazobenzene 60-11-7 Dye, laboratories
trans-2-[(Dimethylamino)methylimino]-5-[2-
(5-nitro-2-furyl)- 25962-77-0 Limited usage as a
vinyl]-1,3,4-oxadiazole pharmaceutical
/21.,p.148/
2,6-Dimethylaniline (2,6-Xylidine) (1993) 87-62-7 Synthesis of
other chemicals
/1.,p.142/
3,3'-Dimethylbenzidine (ortho-Tolidine) 119-93-7 Dye, laboratories
Dimethylformamide (1989) 68-12-2 Solvent for liquids
and organic compounds
1,1-Dimethylhydrazine 57-14-7 Rocket fuel
formulations, chemical
synthesis /3.,p.149/
1,2-Dimethylhydrazine 540-73-8 Chemical intermediate
/19.,p.146/
1,6-Dinitropyrene (1989) 42397-64-8 Diesel and gasoline
engine exhaust fumes
/18.,p.216/
1,8-Dinitropyrene (1989) 42397-65-9 Diesel and gasoline
engine exhaust fumes
/18.,p.232/
1,4-Dioxane 123-91-1 Raw material, solvent
Disperse Blue 1 (1990) 2475-45-8 Dye, hair dye
Ethyl acrylate 140-88-5 As a component of
solution for coating
textiles, paper and
leather /1.,p.53/
Ethylene thiourea 96-45-7 Raw material,
laboratories, rubber
industry
Ethyl methanesulfonate 62-50-0 Laboratories
2-(2-Formylhydrazino)-4-(5-nitro-2-
furyl)thiazole 3570-75-0 No use
Glasswool (1988)
Glu-P-1 (2-Amino-6-methyldipyrido
[1,2-a:3',2'-d]imidazole) 67730-11-4 Charred fraction of
cooked fish and meat
/10.,p.37/
Glu-P-2 (2-Aminodipyrido
[1,2-a:3',2'-d]imidazole) 67730-10-3 Charred fraction of
cooked fish and meat
/10.,p.37/
Glycidaldehyde 765-34-4 Acrolein metabolite
Griseofulvin 126-07-8 Antibiotic drug,
veterinary medicine
HC Blue No. 1 (1993) 2784-94-3 Hair dye
Heptachlor (1991) 76-44-8 Pesticide
Hexachlorobenzene 118-74-1 Fungicide
Hexachlorocyclohexanes Pesticide /1.,p.1616/
Hexamethylphosphoramide 680-31-9 Solvent
Hydrazine 302-01-2 Raw material
Indeno[1,2,3-cd]pyrene 193-39-5 Tobacco smoke,
inhalation of polluted
air /17.,p.376/
Iron-dextran complex 9004-66-4 Drug
Lasiocarpine 303-34-4 Used medicinally as an
emetic and in the
treatment of snake
bites /15.,p.282/
Lead [7439-92-1] and lead compounds, inorganic Manufacture of pipes,
cable sheating
/1.,p.1200/
Magenta (containing CI Basic Red 9) (1993) 632-99-5 Dyes and dyestuff
/1.,p.699/
MeA-a-C (2-Amino-3-methyl-9H-pyrido
[2,3-b]indole) 68006-83-7 Grilled food, tobacco
smoke /9.,p.279/
Medroxyprogesterone acetate 71-58-9 Hormones,
pharmaceutical
industry/2.,pp.80-725/
MeIQ (2-Amino-3,4-dimethylimidazo
[4,5-f]quinoline) (1993) 77094-11-2 Grilled beef and fish
/9.,p.279/
MeIQx (2-Amino 3,8-dimethylimidazo
[4,5-f]quinoxaline) (1993) 77500-04-0 Fried fish and beef
/9.,p.279/
Merphalan 531-76-0 Antineoplastic agent
2-Methylaziridine 75-55-8 Intermediate
Methylazoxymethanol acetate 592-62-1 Cancer research
5-Methylchrysene 3697-24-3 Diesel and gasoline
engine exhaust fumes
/18.,p.32/
4,4'-Methylene bis(2-methylaniline) 838-88-0 Dye manufacture /22/
4,4'-Methylenedianiline (4,4'-
Diaminodiphenylmethane) 101-77-9 Production of
isocyanates and
polyisocyanates
/1.,p.144/
Methylmercury compounds (1993)
Methyl methanesulfonate 66-27-3 Produced for research
purposes
2-Methyl-1-nitroanthraquinone
(uncertain purity) 129-15-7 Dye intermediate
/2.,pp.82-1639/
N-Methyl-N-nitrosourethane 615-53-2 Laboratory chemical
/10.,p.213/
Methylthiouracil 56-04-2 Antineoplastic agent
Metronidazole 443-48-1 Drug
Mirex 2385-85-5 Pesticides
/1.,p.1616/
Mitomycin C 50-07-7 Antineoplastic agent
Monocrotaline 315-22-0 Consumptions of
extracts of crotalaria
species as bush teas
5-(Morpholinomethyl)-3-[(5-
nitrofurfurylidene)amino]-2-oxazolidinone 3795-88-8 Former drug /22/
Nafenopin 3771-19-5 Drug /22/
Nickel, metallic (1990) 7440-02-0 Manufacture of acid-
resisting and magnetic
alloys /1.,p.1438/
Nitridazole 61-57-4 Drug
Nitrilotriacetic acid and its salts (1990) 139-13-9 Softener in cleaning
agents and phosphate
substitute in
detergents /23.,p.119/
5-Nitroacenaphthene 602-87-9 Diesel exhaust
/3.,p.215/
6-Nitrochrysene (1989) 7496-02-8 Gasoline and diesel
engine exhaust fumes
/2.,90-252/
Nitrofen, technical-grade 1836-75-5 Herbicide
2-Nitrofluorene (1989) 607-57-8 Gasoline and diesel
engine exhaust fumes
/2.,90-252/
1-[(5-Nitrofurfurylidene)amino]-2-
imidazolidinone 555-84-0 Former drug
/21.,p.182/
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide 531-82-8 Analgesics,
anti-inflammatory
agent /24.,p.34/
Nitrogen mustard N-oxide 126-85-2 Intermediate in
production of
antineoplastic drugs
2-Nitropropane 79-46-9 Use in vinyl epoxy
paints, printing inks,
adhesives
1-Nitropyrene (1989) 5522-43-0 Diesel engine exhaust
fumes /18.,p.232/
4-Nitropyrene (1989) 57835-92-4 Laboratory chemical
N-Nitrosodi-n-butylamine 924-16-3
N-Nitrosodiethanolamine 1116-54-7 Isolated from cosmetic
products /1.,p.1235/
N-Nitrosodi-n-propylamine 621-64-7 Isolated in some
pesticides /6.,p.179/
3-(N-Nitrosomethylamino)propionitrile 60153-49-3 Constitutent of betel
nut
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-
1-butanone (NNK) 64091-91-4 Tobacco smoke
/25.,pp.209...223/
N-Nitrosomethylethylamine 10595-95-6 Tobacco smoke
/26.,p.222/
N-Nitrosomethylvinylamine 4549-40-0 Apple brandy
/26.,p.258/
N-Nitrosomorpholine 59-89-2 Rubber industry
N'-Nitrosonornicotine 16543-55-8 Tobacco smoke
/2.,pp.85-128/
N-Nitrosopiperidine 100-75-4 Fried meat and fish,
rubber /26.,p.289/
N-Nitrosopyrrolidine 930-55-2 Tobacco smoke, fried
meat and fish
/26.,p.314/
N-Nitrososarcosine 13256-22-9 Fried meat
/26.,p.328/
Ochratoxin A (1993) 303-47-9 Mycotoxin
/2.,pp.91-221/
Oil Orange SS 2646-17-5 Dye
Panfuran S, containing
dihydroxymethylfuratrizine 794-93-4 Drug
Pentachlorophenol (1991) 87-86-5 Pesticide
Phenazopyridine hydrochloride 136-40-3 Drug /4.,p.312/
Phenobarbital 50-06-6 Drug /4.,p.312/
Phenoxybenzamine hydrochloride 63-92-3 Drug /27/
Phenyl glycidyl ether (1989) 122-60-1 Epoxy compounds
Phenytoin 57-41-0 Drug /5.,II/47/
PhIP (2-Amino-1-methyl-6-phenylimidazo
[4,5-b]pyridine) (1993) 105650-23-5 Cooked food, tobacco
smoke /22/
Ponceau MX 3761-53-3 Dye
Ponceau 3R 3564-09-8 Dye
Potassium bromate 7758-01-2 Flour milling
industries as additive
to improve baking
properties
/2.,pp.82-697/
Progestins Drugs
1,3-Propane sultone 1120-71-4 Sulfopropylation of
organic compounds
/1.,p.121/
b-Propiolactone 57-57-8 Used in organic
synthesis, vapour
sterillant,
disinfectant /1.,p.1185/
Propylthiouracil 51-52-5 Antineoplastic agent
Rockwool (1988)
Saccharin 81-07-2 Artificial sweeteners
/28.,p.111/
Safrole 94-59-7 Parfumery, soaps,
flavouring agent in
drugs /15.,p.234/
Slagwool (1988)
Sodium ortho-phenylphenate 132-27-4 Fungicide
/2.,pp.84-1614/
Sterigmatocystin 10048-13-2 Mycotoxin
Streptozotocin 18883-66-4 Drug
Styrenee 100-42-5 Solvent, raw material
Sulfallate 95-06-7 Herbicide
2,3,7,8-Tetrachlorodibenzo-para-dioxin
(TCDD) 1746-01-6 By-product during the
synthesis of 2,4,5-
trichlorophenol
/1.,p.638/
Tetrachloroethylene 127-18-4 Dry cleaning/1.,p.677/
Thioacetamide 62-55-5 Use as an analytical
reagent in the
laboratory /1.,p.1391/
4,4'-Thiodianiline 139-65-1 Dye intermediate
/27.,p.152/
Thiourea 62-56-6 Photocopying, raw
material
Toluene diisocyanates 26471-62-5 Manufacture of
elastomers of
polyuretane/1.,p.1161/
ortho-Toluidine 95-53-4 Dye
Trichlormethine (Trimustine hydrochloride)
(1990) 817-09-4 Antineoplastic agent
/2.,pp.91-574/
Trp-P-1 (3-Amino-1,4-dimethyl-5H-
pyrido[4,3-b]indole) 62450-06-0 Charred fraction of
cooked fish and meat
/10.,p.252/
Trp-P-2 (3-Amino-1-methyl-5H-
pyrido[4,3-b]indole) 62450-07-1 Charred fraction of
cooked fish and meat
/10.,p.252/
Trypan blue 72-57-1 Dye
Uracil mustard 66-75-1 Antineoplastic agent
Urethane 51-79-6 Raw material
Mixtures
Bitumens, extracts of steam-refined and
air-refined 8052-42-4
Carrageenan, degraded 9000-07-1 Food additive
Chlorinated paraffins of average carbon chain length C12 and
average degree of chlorination approximately 60% (1990)
Coffee (urinary bladder) (1991)
Diesel fuel, marine(e) (1989)
Engine exhaust, gasoline (1989)
Fuel oils, residual (heavy) (1989)
Gasoline(e) (1989)
Pickled vegetables (traditional in Asia)
(1993)
Polybrominated biphenyls (Firemaster
BP-6) 59536-65-1 Flame
retardant
Toxaphene (Polychlorinated camphenes) 8001-35-2 Pesticide
Toxins derived from Fusarium moniliforme
(1993) Mycotoxins
Welding fumes (1990)
Exposure circumstances
Carpentry and joinery
Textile manufacturing industry (work in) (1990)
________________________________________________________________________________
(a) Year in brackets: year in which the evaluation was published
subsequent to the Supplement 7 Working Group for agents,
mixtures and exposure circumstances considered in Volumes 43-58
of the Monographs.
(b) This evaluation applies to the group of chemicals as a whole and not
necessarily to all individual chemicals within the group.
(c) There is also conclusive evidence that these agents have a protective
effect against cancers of the ovary and endometrium.
(d) Overall evaluation upgraded from 2B to 2A with supporting evidence from
other relevant data.
(e) Overall evaluation upgraded from 3 to 2B with supporting evidence from
other relevant data.
(f)List of references:
1. ILO Encyclopedia of Occupational Safety and Health, 3th editon, 1983
2. CIS-ILO Microfiche-Collection
3. Kellard., B., Hazardous Substances -Carcinogenic Guide, Croner
Publication Ltd, Croner House, London, UK, 1991
4. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Overall Evaluation of Carcinogenety, supp.7, 1987
5. International Program of Chemical Safety/International Register of
Potentially Toxic Chemicals, Computerized Listing of Chemicals Being
Tested for Toxic Effects, UNEP/ILO/WHO, August 1990
6. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol.17,
1978
7. Canadian Centre for Occupational Health and Safety, Material Safety Data-
Sheets (MSDS/FTSS) CD-INFO Disqs, 93-2
8. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Chemicals used in Plastics and Elastomers, vol.39, 1986
9. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Naturally Occuring Toxins and Synthetic Food Components etc.,
vol.40, 1986
10. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Food Additives, Feed Additives and Naturally Occuring Substances,
vol.31, 1983
11. The Merck Index, An Encyclopedia of Chemicals and Drugs, 9th edition, 1976
12. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans,
vol.50, 1991
13. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Aromatic Amines and Related Nitro Compounds, Hair Dyes, etc.,
vol.16, 1978
14. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Aromatic Amines, Antraquinones etc., vol.27,1982
15. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Some Naturally Occuring Substances, vol.10, 1976
16. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans -
Pharmaceutical Drugs, vol.50, 1990
17. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans,
vol.31, 1989
18. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans from
Diesel and Some Nitroarenes, vol.46,1989
19. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans,
vol.4,1974
20. IARC Monographs on the Evaluation of Carcinogenic risks to humans -
Allyl Compounds, Aldehyds, Epoxides and Peroxides, vol 36, 1985
21. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans,
vol.7, 1974
22. Silver Platter cancer CD, 1993
23. Nordic Councils of Ministers, Effects on Reproduction of Chloroform and
1,2-Dibromo-3-Chloropropene, Swedish National Chemicals Inspectorate,
Solna, Sweden, 1992
24. IARC Monographs on the Evaluation of Carcinogenic risks to humans -
Some Nitroso Compounds, vol.40, 1990
25. IARC Monographs on the Evaluation of Carcinogenic risks to humans -
Polynuclear Aromatic Compounds etc., vol.37, 1985
26. Canadian Centre of Occupational Safety and Health, CD-INFO disq
series: NIOSHTIC(R), 1993
27. IARC Monographs on the Evaluation of Carcinogenic risks to humans,
vol. 27, 1987
28. IARC Monographs on the Evaluation of Carcinogenic risks to humans,
vol. 22, 1980
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Updated by AS. Approved by EC. Last update: 30.11.2004.